Fundamentals of Immunology: T Cells and Signaling

This specialization is designed to equip students with the basic concepts and vocabulary of immunology. The goal is to provide students from different backgrounds with a fundamental understanding of immunology and the ability to appreciate and analyze new developments in immunological therapies designed for the treatment of disease.

Created by: Alma Moon Novotny

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Overall Score : 100 / 100

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Course Description

Course 2 of a three course specialization called Fundamentals of Immunology. Each course in the specialization presents material that builds on the previous course's material.This is the second half of the journey through the defenses your body uses to keep you healthy. In the first part we learned about innate immunity and B cell function. The second part covers T cell function and coordination of the immune response.Fundamentals of Immunology: T cells and Signaling builds on the first course to describe the functions of Complement, MHC presentation to T cells, T cell development and signaling. The early lectures survey cells, tissues and organs using metaphors, cartoons and models to improve understanding and retention. This course includes the structure of both MHC proteins and T cell receptors and the sources of variation. The course provides animations of gene rearrangement, developmental processes and signal cascades. Testing employs multiple choice questions testing facts, concepts, and application of principles. Questions may refer to diagrams, drawing and photographs used in lecture and reproduced in the outline.What You'll Learn:How complement uses adaptive and innate triggers to target pathogens. The detailed structure and coding of MHC proteins and both alpha-beta and gamma delta receptors and how these proteins interact to initiate an adaptive immune response. The basics of signaling, and the varieties of external receipt and internal activation pathways. We bine the process of putting together how signals and crosstalk control the activity of the immune system.

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Instructor Details

Alma Moon Novotny

Alma Novotny earned her PhD from Purdue University in Developmental logy under the direction of Michael Forman. She has taught college courses for over forty years in plant and animal sciences, genetics and introductory, cell and developmental biology. She has also written test question banks and contributed questions to both the MCAT and the GRE Advanced Exam in chemistry, Cell and Molecular logy. Since joining Rice University in 2000, she has taught immunology and is a three-time recipient of the George R. Brown Award for Superior Teaching.

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Reviews

5.0

5 total reviews

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By David B on 15-Feb-19

This was a very amazing course. The teacher is very good! She explains everything in a very interesting way. Immunology can be confusing but she somewhat make it easy to remember. I liked the "artsy" proteins and things she used to explain. I also liked the organization of the course. I would suggest improving a little bit the video and sound, and adding some animations, for example for signaling or conformation changes. I would recommend you to take this course if you want to understand more about T cells and overall immunology terminology. The "level" wasn't that hard but it was not easy. You need some kind of biology/biochemistry knowledge to acquire most of the info.

By Ahmed A E A on 9-Mar-19

excellent

By CARLOS K A D P F on 11-Mar-19

Very nice <3

By kristin v r on 30-Apr-19

Great course. Great Professor.

By Tayren N B on 12-Aug-19

Excellent all around!