Fundamentals of Immunology: Innate Immunity and B-Cell Function
This specialization is designed to equip students with the basic concepts and vocabulary of immunology. The goal is to provide students from different backgrounds with a fundamental understanding of immunology and the ability to appreciate and analyze new developments in immunological therapies designed for the treatment of disease.
Created by: Alma Moon Novotny
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Overall Score : 94 / 100
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Course Description
Course 1 of a three course specialization called Fundamentals of Immunology. Each course in the specialization presents material that builds on the previous course's material.This is the first leg of a three-part journey through the defenses your body uses to keep you healthy. In this part we hope to give you the vocabulary and concepts you need to interact with the medical community and to provide them in a context that makes them memorable.Fundamentals of Immunology introduces students to the basic functions of the adaptive and innate immune systems. The early lectures survey cells, tissues and organs using metaphors, cartoons and models to improve understanding and retention. After describing the form, function, origin and varieties of antibodies, subsequent lectures provide details on the mechanism of the generation of variation. The course provides animations of gene rearrangement and class switching and descriptions of affinity maturation correlated with detailed physical models of antibody structure. The final lecture reviews these concepts in anatomical context. Testing employs multiple choice questions testing facts, concepts, and application of principles. Questions may refer to diagrams, drawing and photographs used in lecture and reproduced in the outline.What You'll Learn:The difference between adaptive and innate immune systems, the characteristics of various pathogens that they protect you from and the overall strategies employed in this protection. The detailed structure of antibodies and related immunoglobulin receptors, the characteristics and function of the different antibody classes and the mechanism for producing both the recognition regions and stem regions. Finally, how these structures are coded for in the DNA and expressed in the B cells.
Instructor Details

- 4.7 Rating
97 Reviews
Alma Moon Novotny
Alma Novotny earned her PhD from Purdue University in Developmental logy under the direction of Michael Forman. She has taught college courses for over forty years in plant and animal sciences, genetics and introductory, cell and developmental biology. She has also written test question banks and contributed questions to both the MCAT and the GRE Advanced Exam in chemistry, Cell and Molecular logy. Since joining Rice University in 2000, she has taught immunology and is a three-time recipient of the George R. Brown Award for Superior Teaching.